One corner for the object oriented to be printed out last (angled such to be layered at the end) did not end up with proper edges. The corner had improper layers and a gap/hole in the layers.
This sort of failure mode is typical when the model is not sufficiently supported. With so few supports in the starting corner, your part is actually wobbling as it builds. That wobbling during printing is what causes the skewed geometry. Additional supports will cause the part to stay rigid while printing. You could try increasing the touch point size or the density of the supports, but smart placement will solve the problem too.
Check out these two pictures for what I would recommend. The screenshots are taken from below, with the center representing the bottom tip of the part. The picture on the left is the PreForm defaults. The picture on the right shows my added supports highlighted. Note how the addition of supports at those locations will prevent the part from wobbling.
Having a small vent hole at the bottom may also prevent some of the holes you have on the side walls, especially with your wall thickness being pretty thin.
I would flip the part over so the open side is facing towards the base. Then let PreForm create supports. Then go in and add supports any place they appear to be “sparse”. All the support contact points will be on the interior or along the lip. You’ll be able to sand the lip easily and depending on what you’re using this for you might not need to do anything more than break away the supports from the inside surface.
When I print, I always try to orient the visible faces of my models so they will have the fewest support contact points and then I add extra supports where the blemishes they leave won’t matter.