Can definitely confirm: last 2-3 releases have completely screwed-up the Spacemouse working.
uninstalled Preform
-cleaned all registry entries
-updated Nvidia Quadro drivers to most current
-uninstalled 3D Connexion Spacemouse drivers
-reloaded Preform (re-downloaded)
-restored default setting in the 3D Connexion app
This temporarily worked; as soon as I opened the Spacemouse app to customize the profile for Preform, everything went right back to not working.
At least I get a good long look at the cool new Preform splash graphics while everything hangs. So I guess I’ve got that going for me.